Primary Leiomyosarcoma of the Proximal Tibia

Kitay A, Rybak L, Desai P, Villalobos CE, Wittig JC. Primary leiomyosarcoma of the proximal tibia: case report and review of the literature. Bull NYU Hosp Jt Dis. 2008;66(1):49-53. Leiomyosarcoma is a malignant entity that commonly affects the soft tissues of the body, such as the uterus, gastrointestinal system, and the soft tissues of the extremities. Primary leiomyosarcoma of the bone is a very rare tumor that affects the metaphysis of long bones, especially the distal femur and proximal tibia. Leiomyosarcoma has a radiologic aggressive pattern. The diagnosis is based on microscopic features (elongate and spindled tumor cells) and immumohistochemical and ultrastructural study.